Dibenzosuberyl and dibenzosuberenyl derivatives

Details Dibenzosuberyl and dibenzosuberenyl derivatives Dibenzosuberyl and dibenzosuberenyl derivatives

1993-11-03

1995-08-15

Nutter, Nathan M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564427, 525 5411, 530816, C07C21100

Patent

active

054421225

ABSTRACT:
The present invention is directed to a compound represented by the following formula (I), ##STR1## and a linker for peptide synthesis using the above compound. When the linker of the present invention is used for the solid-phase peptide synthesis, it is possible to synthesize those peptides which are sensitive to acid and difficult to synthesize by conventional methods. Also, side reactions can be prevented, and the desired product is produced at a high purity because cleavage can be achieved under milder conditions or in shorter times. In other words, efficient peptide synthesis is possible.

REFERENCES:
patent: 3052721 (1962-09-01), Bernstein et al.
patent: 3489836 (1970-01-01), Waring
J. Pless, Helvetica Chimica Acta, vol. 59, Fasc. 2 (1976), p. 499 (1976).

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