Compositions – Chemiluminescent
Patent
1994-05-20
1995-07-18
Tucker, Philip
Compositions
Chemiluminescent
25230116, 25230134, 25230135, 548110, 548405, C09K 300, C09K 1106, C09K 1102
Patent
active
054338964
ABSTRACT:
The invention relates to fluorescent dyes that are substituted or unsubstituted derivatives of 1-[isoindolyl]methylene-isoindole that are bound through both isoindole nitrogens to a boron difluoride moiety, forming a fluorescent dibenzopyrrometheneboron difluoride compound ##STR1## whose fluorescence properties are modified by the selection of appropriate chemical substituents.
The dibenzopyrrometheneboron difluoride compound is optionally substituted by hydrogen, halogen cyano, sulfo, alkali or ammonium salts of sulfo, carboxy, substituted or unsubstituted alkyl, perfluoroalkyl, alkoxy, alkylthio, nitro, amino, monoalkylamino, dialkylamino, substituted or unsubstituted aryl substituents, substituted or unsubstituted heteroaryl substituents, or additional substituted or unsubstituted fused benzo rings or substituted or unsubstituted fused heteroaromatic rings. Any alkyl substituent present on the subject dye is optionally further substituted by a reactive site, or a functional group that can be readily converted into a reactive site.
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Haugland Richard P.
Kang Hee C.
Helfenstein Allegra J.
Molecular Probes, Inc.
Skaugset Anton E.
Tucker Philip
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