Dibenzodiazepinone analogues, processes for their production...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C540S495000

Reexamination Certificate

active

07655646

ABSTRACT:
The invention relates to biologically active dibenzodiazepinone analogs represented by Formula I, to methods of producing them, to pharmaceutical compositions comprising them and to methods of treating neoplastic conditions.

REFERENCES:
patent: 3854480 (1974-12-01), Zaffaroni
patent: 4452775 (1984-06-01), Kent
patent: 5039660 (1991-08-01), Leonard
patent: 5393665 (1995-02-01), Fayerman et al.
patent: 5466590 (1995-11-01), Sariaslani et al.
patent: 5523288 (1996-06-01), Cohen et al.
patent: 5541181 (1996-07-01), Ohkuma
patent: 5556772 (1996-09-01), Sorge et al.
patent: 5561122 (1996-10-01), Pettit
patent: 5783561 (1998-07-01), Horwitz et al.
patent: 5830695 (1998-11-01), Serizawa et al.
patent: 6140306 (2000-10-01), Lambert, Jr. et al.
patent: 6423753 (2002-07-01), Dougherty
patent: 6683300 (2004-01-01), Doroshenko
patent: 7257562 (2007-08-01), Farnet et al.
patent: 2003/0109518 (2003-06-01), Lu et al.
patent: 2003/0219718 (2003-11-01), Weber et al.
patent: 2004/0220179 (2004-11-01), Lu et al.
patent: 2248820 (1997-09-01), None
Goodfellow, “Superageneric Classification of Actinomycetes,” Bergey's Manual of Systematic Bacteriology (1989), vol. 4, pp. 2333-2339.
Embley and Stackebrandt, “The Molecular Phylogeny and Systematics of the Actinomycetes,” Annu. Rev. Microbiol., (1994), vol. 48, pp. 257-289.
Zazopoulos et al., “A Genomics-Guided Approach for Discovering and Expressing Cryptic Metabolic Pathways,” Nature Biotechnology (2003), vol. 21, pp. 187-190.
Stryer, Biochemistry 3rdEdition, 1998, W. H. Freeman and Co., New York, pp. 752-754.
Altschul et al., “Basic Local Alignment Search Tool,” Journal of Molecular Biology (1990), vol. 215(3), pp. 403-410.
British Journal of Cancer, 1998, vol. 77(1), pp. 1-11, United Kingdom Coordinating Committee on Cancer Research (UKCCCR) Guidelines for the Welfare of Animals in Experimental Neoplasia (Second Edition).
Yasuhiro Igarashi et al., Revision of the Structure Assigned to the Antibiotic BU-4664L from Micromonopora, J. Antibiot., 2005, vol. 58(5), pp. 350-352.
Correction to Article by Yasuhiro Igarashi et al., Revision of the Structure Assigned to the Antibiotic BU-4664L from Micromonopora, J. Antibiot., 2005, vol. 58(7).
Demain et al., “Manual of Industrial Microbiology and Biotechnology,” American Society for Microbiology, Washington DC, 1986.
Hesketh et al., “A Novel Method for Improving Streptomyces coelicolor A3(2)for Production of rpsL(Encoding Ribosomal Protein S12)Mutations conferring Resistance of Streptomycin,” J. Antibiotics, 1997, vol. 50(6), pp. 532-535.
Hosoya et al., “Acquisition of Certain Streptomycin-resistant(str)Mutations Enhances Antibiotic Production in Bacteria,” Antimicrobial Agents and Chrmotherapy, 1998, vol. 42(8), pp. 2041-2047.
Plater et al., “Synthesis of 1,3,5-tris[4-(dairylamino)phenyl]benzene and 1,3,5-tris(diarylamino)benzene derivative,” J. Chem. Society, Perkin Trans. 1, 2000, pp. 2695-2701.
Hwang et al., “Efficient Synthesis of Phosphorylated Prodrugs with Bis(P0M)-phosphoryl Chloride,” Org. Lett, 2004, vol. 6(10), pp. 1555-1556.
Freireich et al., “Quantitative Comparison of Toxicity of Anticancer Agents in Mouse, Rat, Hamster, Dog, Monkey and Man,” Cancer Chemoth., 1966, vol. 50(4), pp. 219-244.
Workman et al., “Guidelines for the welfare of animals in experimental neoplasia,” United Kingdom Coordinating Committee on Cancer Research (UKCCCR), British Journal of Cancer, 1977, 2ndEdition, vol. 77, pp. 1-10.
Premont et al., “[3H]Norepinephrine Binding by rat glial cells in culture. Lack of correlation between binding and adenylate cyclase activation,” Biochim Biophys. Acta., 1975, vol. 381, pp. 368-376.
March et al., Advanced Organic Chemistry, John Wiley and Sons, Inc. pp. 404, (1991).
Silverberg et al., “A simple, rapid and efficient protocol for the selective phosphorylation of phenols with dibenzyl phosphate,” Tetrahedron Letters, 1996, vol. 37, pp. 771-774.
Charan et al., “A new antimicrobial alkaloid from a micromonospora sp.,” Abstract and figures from Poster P:157, presentation of the 44thAnnual Meeting of the American Society of Pharmacognosy, Chapel Hill, NC, 2003, pp. 209.
Takagi et al., “A gene cluster for the mevalonate pathway from Streptomyces sp. Strain CL190,” Journal of Bacteriology, 2000, vol. 182(15), pp. 4153-4157.
Carrillo et al., “The multiple sequence alignment problem in biology,” Applied Math, 1998, vol. 48(5), pp. 1073-1082.
Murakami et al., “Thiostrepton-induced gene expression in Streptomyces Lividans,” Journal of Bacteriology, 1989, vol. 171(3), pp. 1459-1466.
Thompson et al., “Cloning of antibiotic resistance and nutritional genes in Streptomycetes,” Journal of Bacteriology, 1982, vol. 151(2), pp. 668-677.
Hopwood et al., “Plasmid and phage vectors for gene cloning and analysis in Streptomycetes,” Methods in Enzymology, 1987, vol. 153, pp. 116-166.
Nielson et al., “Taq extender PCR additive for improved length, yield, and reliability of PCR products,” Strategies, 1994, vol. 7, pp. 27.
Matteucci et al., “Synthesis of deoxyoligonucleotides on a polymer support,” American Chemical Society, 1981, vol. 130(11), pp. 3185-3191.
Gluzman et al., “SV40-transformed simian cells support the replication of early SV40 mutants,” Cell, 1981, vol. 23(1), pp. 175-182.
Vaara, “Agents that increase the permeability of the outer membrane,” Microbiological Reviews, 1992, vol. 56(3), pp. 395-411.
Tsubery et al., “Structure-function studies of polymyxin B nonapeptide: Implications to sensitization of gram-negative bacteria,” Journal of Medical Chemistry, 2000, vol. 43(16), pp. 3085-3092.
Carter et al., “5-Lipoxygenase inhibitory activity of zileuton,” Journal of Pharmacology and Experimental Therapeutics, 1991, vol. 256(3), pp. 929-937.
Safayhi et al., “Concentration-dependent potentiating and inhibitory effects of boswellia extracts on 5-Lipoxygenase product formation in stimulated PMNL,” Planta Medica, 2000, vol. 66(2), pp. 110-113.
Dimitradou et al., “Identification and characterization of a new cytotoxic agent from actinomycetes,” Poster Presentation Presented at the AACR Annual Meeting, Orlando, FL, Mar. 27 to 31, 2004.
Charan et al., “Diazepinomicin, a new antimicrobial alkaloid from a marine Micromonospora sp.,” J. Nat. Prod., 2004, vol. 67(8), pp. 1431-1433.
Berge et al., “Pharmaceuticals salts,” Journal of Pharmaccutical Scicnccs, 1977, vol. 66(1), pp. 1-19.
Rooseboom et al., “Enzymed-catalyzed activation of Anticancer prodrugs,” Pharmacol. Rev., 2004, vol. 56, pp. 53-102.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Dibenzodiazepinone analogues, processes for their production... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Dibenzodiazepinone analogues, processes for their production..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dibenzodiazepinone analogues, processes for their production... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4180016

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.