Dibenzo[b,d]thiopyran derivatives, pharmaceutical composition an

Details Dibenzo[b,d]thiopyran derivatives, pharmaceutical composition an Dibenzo[b,d]thiopyran derivatives, pharmaceutical composition an

1986-03-04

1986-11-25

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514231, 514252, 514324, 514422, 514437, 544 584, 544 587, 544145, 544364, 544375, 546202, 548525, 549 26, A61K 3138, A61K 31535, C07D 3510, C07D41312

Patent

active

046249494

ABSTRACT:
The invention relates to compounds having the general formula (I) ##STR1## wherein R.sub.1 is carboxy, esterified carboxy or an amide of formula ##STR2## in which R.sub.9 is hydrogen or C.sub.1 -C.sub.6 alkyl, A is C.sub.2 -C.sub.6 alkylene and R.sub.a and R.sub.b are hydrogen or C.sub.1 -C.sub.6 alkyl or R.sub.a and R.sub.b taken together with the nitrogen atom to which they are linked form a saturated, optionally substituted, heteromonocyclic ring;

REFERENCES:
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U.S. Pat. No. 3,944,673 (Farmdoc 24298X) Eli Lilly Co.
Belgian Pat. No. 823,873 (Farmdoc 34237W) Farmitalia Carlo Erba Spa.
Belgian Pat. No. 890,773 (Farmdoc 35242E) Farmitalia Carlo Erba SpA.
U.S. Pat. No. 4,166,062 (Farmdoc 67882B) Upjohn Co.
U.S. Pat. No. 4,179,510 (Farmdoc 01677C) Upjohn Co.
Belgian Pat. No. 871,702 (Farmdoc 33369B) Upjohn Co.
Aust. J. Chem. 1983, 36(4), 795-802 (Chemical Abstracts 99:13970w).
J. Chem. Soc. Perkin Trans 1, 1982, (4), 91722 (Chemical Abstracts 97:55648a).
Japan Kokai JJ 1138-680 (Farmdoc 04559Y) Grelan Pharmaceutical KK.
Japan Kokai J5 2105-174 (Farmdoc 73604Y) Grelan Pharmaceutical KK.
Japan Kokai J5 5149-300 (Farmdoc 04916D)Grelan Pharmaceutical KK.

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