Dibenzo[b,d]pyranyloxyaminopropanols

Details Dibenzo[b,d]pyranyloxyaminopropanols Dibenzo[b,d]pyranyloxyaminopropanols

1985-06-27

1986-02-11

Ramsuer, Robert W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544 587, 544375, 546196, 548262, 548336, 548374, 548525, 549280, 549390, 2603309, C07D31180, C07D41312

Patent

active

045699941

ABSTRACT:
Dibenzopyran derivatives which possess antihypoxia activity are 7,8,9,10-tetrahydro-6H-dibenzo[b,d]pyranyloxyaminopropanols having the formula: ##STR1## Where X is oxygen or dialkyl in which each alkyl group contains one to seven carbons (C.sub.1 -C.sub.7); R is hydrogen or alkyl containing one to seven carbons (C.sub.1 -C.sub.7); and A is --NR.sub.1 R.sub.2 where R.sub.1 and R.sub.2 may independently be hydrogen, C.sub.1 -C.sub.7 alkyl, C.sub.3 -C.sub.7 cycloalkyl, phenyl, C.sub.7 -C.sub.10 phenylalkyl, C.sub.7 -C.sub.10 phenoxyalkyl, C.sub.2 -C.sub.6 alkanol, 6-oxo-6H-dibenzo[b,d]pyran-3-yl, 2-hydroxy-3-(7,8,9,10-tetrahydro-6-oxo-6H-dibenzo[b,d]pyranyl-3-oxy)-propy l; or A is a heterocyclic ring of structure: ##STR2## where n=2 or 3; or A is a substituted heterocyclic ring of structure: ##STR3## where Y and Z may be independently hydrogen or methyl and B represents a single bond, methylene, ethylene, propylene, CH-phenyl, CHCH.sub.2 -phenyl, oxygen, sulfur, or N--R.sub.4 where R.sub.4 is hydrogen, C.sub.1 C.sub.4 alkyl, formyl, phenyl, or benzyl and where the phenyl rings may additionally be substituted with halogen, methoxy, methyl, CF.sub.3, or various combinations thereof; or where A is an unsaturated heterocyclic ring taken to be 1-imidazolyl, 1-pyrrolyl, 1-pyrazolyl or 1-[1,2,4-triazolyl].

REFERENCES:
patent: 3649650 (1972-03-01), Razdan et al.

Affiliated with

Also associated with

Rating

Dibenzo[b,d]pyranyloxyaminopropanols does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Dibenzo[b,d]pyranyloxyaminopropanols, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dibenzo[b,d]pyranyloxyaminopropanols will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1206408