Dibenzo (a,d) cycloheptene derivatives

Details Dibenzo (a,d) cycloheptene derivatives Dibenzo (a,d) cycloheptene derivatives

1975-03-07

1976-08-17

Hines, Robert V.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602471R, 2602475R, 260268TR, 26029356, 26032682, 26032687, 2603409, 260465R, 260465F, 260465G, 260469, 260470, 260473F, 260515R, 260515A, 260516, 260544C, 260557B, 260558R, 260558D, 2605585, 260559R, 424324, C07C10320, C07C10376

Patent

active

039754375

ABSTRACT:
Dibenzo[a,d]cycloheptene derivatives of the formula: ##SPC1##
Wherein x represents hydrogen, halogen, alkyl, alkoxy, alkylthio or trifluoromethyl, R.sub.1 and R.sub.2 represent hydrogen or alkyl, and R.sub.3 represents hydroxy, alkoxy, 4-(2,4-dimethyl-1,3-dioxolanyl)-methoxy, or a group --NR.sub.4 R.sub.5 in which R.sub.4 and R.sub.5 represents hydrogen, alkyl, hydroxyalkyl or phenyl, or --NR.sub.4 R.sub.5 represents a mononuclear 5- or 6-membered heterocyclic group containing a second hetero atom selected from oxygen, sulphur, and nitrogen which is optionally substituted by alkyl, said alkyl, alkoxy, alkylthio and hydroxyalkyl radicals containing 1 to 4 carbon atoms, are new compounds possessing pharmacological properties, more particularly analgesic, antipyretic and anti-inflammatory properties.

REFERENCES:
patent: 3754021 (1973-08-01), Shen et al.
patent: 3829467 (1974-08-01), Diamond et al.
patent: 3856857 (1974-12-01), Beregi et al.
patent: 3868414 (1975-02-01), Shen et al.
"Tricyclic Compounds", Allais et al., CA78: 111018s (1973).
"Tricyclic Imines", Dostert et al., CA77: 19451j (1972).

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