Dibekacin derivatives and arbekacin derivatives active against r

Details Dibekacin derivatives and arbekacin derivatives active against r Dibekacin derivatives and arbekacin derivatives active against r

1995-09-08

1997-04-08

Peselev, Elli

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 137, 536 138, 536 139, 536 185, A61K 3170

Patent

active

056187955

ABSTRACT:
As new dibekacin derivatives and new arbekacin derivatives are now provided 2"-amino-2"-deoxydibekacin, 2"-amino-5,2"-dideoxydibekacin, 2"-amino-2"-deoxyarbekacin, 2"-amino-5,2"-dideoxyarbekacin, 2"-amino-5,2"-dideoxy-5-epi-fluoroarbekacin and 2"-amino-5,2"-dideoxy-5-epi-aminoarbekacin which all exhibit high antibacterial activity against a wide variety of gram-positive and gram-negative bacteria, including resistant bacteria such as methicillin-resistant Staphylococcus aureus and which are of low toxicity to mammals and are useful as antibacterial agent for treatment of bacterial infections.

REFERENCES:
patent: 4107424 (1978-08-01), Umezawa et al.
patent: 4156078 (1979-05-01), Umezawa et al.
patent: 4187372 (1980-02-01), Carney et al.
patent: 4873225 (1989-10-01), Umezawa et al.

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