Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-06-14
2011-06-14
Kifle, Bruck (Department: 1622)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C540S457000
Reexamination Certificate
active
07960420
ABSTRACT:
Diazonamide A analogs, and the salts, esters and conjugates thereof, having improved aqueous solubility are provided. Also provided are pharmaceutical compositions, and methods for preparing and using such compounds and compositions for the treatment of proliferative diseases.
REFERENCES:
patent: 4261989 (1981-04-01), Sasaki et al.
patent: 5387584 (1995-02-01), Schnur
patent: 5624677 (1997-04-01), El-Rashidy et al.
patent: 5932566 (1999-08-01), Schnur et al.
patent: 7022720 (2006-04-01), Harran et al.
patent: 2006/0089397 (2006-04-01), Harran et al.
patent: 2007/0149583 (2007-06-01), Harran et al.
patent: 2009/0005572 (2009-01-01), Hanson et al.
patent: WO-02/036075 (2002-05-01), None
patent: WO-03/106438 (2003-12-01), None
patent: WO-2005/028434 (2005-03-01), None
patent: WO-2008/154441 (2008-12-01), None
Berge et al., J. Pharm. Sci. (1977) 66:1-10.
Cheung et al., Bioorg. Med. Chem. Lett. (2005) 15:3338-3343.
Chiosis et al., ACS Chemical Biology (2006) 1(5):279-284.
Cruz-Monserrate et al., Mol. Pharmacol. (2003) 63:1273-1280.
Hellman, Cancer: Principles and Practice of Oncology (1993) 4thed. vol. 1 248-275.
Lindquist et al., JACS (1991) 113:2303-2304.
Moulin et al., JACS (2005) 127:6999-7004.
Soga et al., Curr. Cancer Drug Targets (2003) 3:359-369.
Yamamoto et al., Angew. Chem. (2003) 42:1280-1284.
Dabydeen et al. Comparison of the Activities of the Truncated Halichondrin B Analog NSC 707389 (E7389) with Those of the Parent Compound and a Proposed Binding Site on Tubulin, Mol Pharm 70, 1866-75, 2006.
International Search Report and Written Opinion in counterpart PCT/US2008/87783, 2008.
Hanson Gunnar James
Wei Qi
Zhou Ming
Joyant Pharmaceuticals, Inc
Kifle Bruck
Osman Richard Aron
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