Diazoluminomelanin and a method for preparing same

Details Diazoluminomelanin and a method for preparing same Diazoluminomelanin and a method for preparing same

1990-03-07

1991-03-26

Higel, Floyd D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Azo

424 11, 424 9, 435 72, 435 75, 435 78, 435968, 436164, 436172, 436501, 436514, 436518, 436805, 514150, 524198, 534769, 534767, 534789, 534790, C07C24500, C09B 3900, A61B 500

Patent

active

050030507

ABSTRACT:
A water-soluble luminescent compound having repeating units of the formula: ##STR1## The product, which is a polymer having repeating units comprising diazo-linked luminol and hydroxyindole, is referred to as diazoluminomelanin (DALM), since one of the precursors to this product, 3-amino-L-tyrosine (3AT) is closely related to the biological substrates which are converted into melanin.
Also provided is a method for preparing DALM which comprises reacting 3AT with an alkali metal nitrite, and reacting the resulting diazonium salt with luminol.
DALM can be used for chemiluminescent immunoassays for biological and chemical agents; in radiofrequency and ionizing radiation dosimeters; and for RNA/DNA hybridization assays for viruses and genetic detection.

REFERENCES:
patent: 4619990 (1986-10-01), Elmasry et al.
patent: 4743541 (1988-05-01), Higgins et al.
patent: 4745077 (1988-05-01), Holian et al.
patent: 4748116 (1988-05-01), Simonsson et al.
patent: 4765961 (1988-08-01), Schiff et al.
patent: 4766150 (1988-08-01), Kiel
patent: 4788142 (1988-11-01), Hosaka et al.
Drain et al, Chemical Abstracts, vol. 83, #10878v (1975).
Savin et al, Chemical Abstracts, vol. 68, #69638k (1968).

Affiliated with

Also associated with

Rating

Diazoluminomelanin and a method for preparing same does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Diazoluminomelanin and a method for preparing same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Diazoluminomelanin and a method for preparing same will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-618086