Diazepine containing dual action inhibitors

Details Diazepine containing dual action inhibitors Diazepine containing dual action inhibitors

1996-06-19

1997-07-08

Grumbling, Matthew V.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540489, 540527, 540524, 540488, 540490, 540523, 540492, 544 54, 544 47, 544 90, 546138, C07D48704, C07D51304, A61K 3155

Patent

active

056462760

ABSTRACT:
Compounds of the formula ##STR1## wherein X.sub.1 is ##STR2## are disclosed as possessing inhibotory activity against angiotensin converting enzyme (ACE) and neutral endopeptidase (NEP) and thus being useful as cardiovascular agents.

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