Diazaditwistanes, and pharmaceutical compositions for treating p

Details Diazaditwistanes, and pharmaceutical compositions for treating p Diazaditwistanes, and pharmaceutical compositions for treating p

1978-07-20

1980-11-04

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546 63, A61K 3147, C07D47108

Patent

active

042320267

ABSTRACT:
Certain 2- and/or 9- phenylalkyl-5,11-dimethyl-5,11-diazaditwistane compounds bind to opiate receptor sites and have central nervous system activities exemplified by analgesia.

REFERENCES:
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patent: 3931189 (1976-01-01), Langbein et al.
patent: 4033968 (1977-07-01), ten Broeke et al.
Noller, Chemistry of Organic Compounds, 3rd ed., W. B. Saunders Co., Philadelphia (1965), pp. 164, 236, 238-239.
Liberatore, et al., Tetrahedron Letters, no. 26, pp. 2381-2384 (1971).
Hirao, et al., J. Chem. Soc., Chem. Comm., pp. 691-692 (1974).
ten Broeke, et al., J. Org. Chem., vol. 41, pp. 3159-3163 (1976).
Fisher, et al., J. Med. Chem., vol. 20, pp. 63-66 (1977).
Cardillo, et al., Chemical Abstracts, vol. 71, 112538d (1969).
Thiele, Chemical Abstracts, vol. 76, 45914m (1972).
Brown, et al., Chemical Abstracts, vol. 82, 57536b (1975).
Fuson, "Reactions of Organic Compounds", John Wiley & Sons, Inc., New York (1964), p. 571.

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