Diastereoisomers of n.sup.6 -endo-bicyclo[2.2.1]heptyladenosine

Details Diastereoisomers of n.sup.6 -endo-bicyclo[2.2.1]heptyladenosine Diastereoisomers of n.sup.6 -endo-bicyclo[2.2.1]heptyladenosine

1987-05-13

1989-06-06

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 45, 514 47, 536 24, 536 26, A61K 3170, C07H 19167

Patent

active

048372072

ABSTRACT:
(1R-endo) or (1S-endo)-N-bicyclo[2.2.1]heptyl adenosine and pharmaceutically acceptable acid addition salts having highly desirable antihypertensive properties and unexpected A.sub.1 and A.sub.2 receptor binding activity, processes for their manufacture and pharmaceutical compositions and methods for using said compounds and compositions.

REFERENCES:
patent: 3838147 (1974-09-01), Pohlke et al.
patent: 4714697 (1987-12-01), Trivedi
Ts'O (editor) "Basic Principles in Nucleic Acid Chemistry", vol. 1, Academic Press, N.Y., 1974, pp. 115, 159 and 160.
U.S. Ser. No. filed 9-9-85.
EPO Search Report with attachments.

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