Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Silicon containing doai
Reexamination Certificate
2011-08-30
2011-08-30
Chandrakumar, Nizal (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Silicon containing doai
C514S428000, C514S312000, C548S365100, C544S182000
Reexamination Certificate
active
08008278
ABSTRACT:
This invention provides compounds of formula I:wherein R1, R2, R3, R4, R5, R6, R7, Ar1, Ar2, E, a, b, c and z are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The compounds of this invention possess both β2adrenergic receptor agonist and muscarinic receptor antagonist activity and therefore, such compounds are useful for treating pulmonary disorders, such as chronic obstructive pulmonary disease and asthma.
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Hughes Adam
Mammen Mathai
Chandrakumar Nizal
Hagenah Jeffrey A.
Theravance Inc.
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