Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-09-22
1990-09-18
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514317, 546236, 548574, C07D20704, C07D21104, A61K 31445, A61K 3140
Patent
active
049579274
ABSTRACT:
1-[(diarylmethoxy)alkyl]pyrrolidines and piperidines represented by the following formula: ##STR1## wherein X is hydrogen or a fluorine atom, Alk is a linear-chain or branched alkyl group having two or three carbon atoms; R.sub.1 and R.sub.2 are hydrogen or a linear-chain or branched alkoxy radical having 1 to 4 carbon atoms; n is 4 or 5.
The compounds can be used as cardiovascular medicines.
REFERENCES:
patent: 4202896 (1980-05-01), Gouttes
March, Advanced Organic Chemistry, 2nd Ed., pp. 382 and 1122, McGraw-Hill Pub., 1979.
Chemical Abstracts, vol. 101, 1984, p. 37, No. 65725p, E. Lardner et al.: "Hoe 263, a new substance with calcium channel antagonistic activity".
Barbanton Jacques
Chavernac Gilles
Depin Jean-Claude
Ferrand Gerard
Lipha Lyonnaise Industrielle Pharmaceutique
McKane Joseph K.
Rotman Alan L.
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