Diarylalkanoids having activity as lipoxygenase inhibitors

Details Diarylalkanoids having activity as lipoxygenase inhibitors Diarylalkanoids having activity as lipoxygenase inhibitors

1991-08-27

1993-01-05

Dees, Jose

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

560 35, 560 53, 562440, 564265, 568325, C07C 5990, C07C 6232

Patent

active

051772590

ABSTRACT:
The present invention is novel diarylalkanoids having activity as lipoxygenase inhibitors, novel pharmaceutical compositions therefor, and novel methods of use in treating asthma, allergies, cardiovascular diseases, migraines, psoriasis and immunoinflammatory diseases for diarylalkanoids. The compounds of this invention are also useful as cytoprotective agents.

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CA 92:18078lm Page 615 (1980).
Itokawa et al, "Synthesis of Diaryheptanoids and Assessment of Their Pungency", Chemical & Pharmaceutical Bulletin, 31 (7), pp. 2491-2496 (1983).

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