Diaryl substituted thiazoles useful in the treatment of fungal i

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548201, 548202, 548203, 548204, 548205, A61K 31426, C07D27728

Patent

active

061567760

ABSTRACT:
Disclosed is a novel class of thiazole, thiadiazole, and oxadiazole compounds which are substituted at their nuclear carbons by aromatic moieties. These compounds exhibit antifungal activity against a variety of fungi including strains which have proven to be resistant to treatment with known antifungal agents such as Fluconazole.

REFERENCES:
patent: 2852385 (1958-09-01), Jones
patent: 4346157 (1982-08-01), Kakuta et al.
patent: 4746669 (1988-05-01), Caldwell et al.
patent: 5342851 (1994-08-01), Sanfilippo et al.
patent: 5474995 (1995-12-01), Ducharme et al.

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