Diaryl substituted pyridinones

Details Diaryl substituted pyridinones Diaryl substituted pyridinones

2005-09-14

2009-12-08

Davis, Zinna N (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S256000, C514S336000, C514S348000, C546S283400, C546S290000, C546S296000, C544S333000

Reexamination Certificate

active

07629363

ABSTRACT:
Disclosed are compounds Formula Iand pharmaceutically acceptable salts thereof, wherein R1, R2, R3/R4, and R5are defined herein. These compounds are useful for treating diseases and conditions caused or exacerbated by unregulated p38 MAP Kinase and/or TNF activity. Pharmaceutical compositions containing the compounds, methods of preparing the compounds and methods of treatment using the compounds are also disclosed.

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