Diamino-androstane derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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514176, A61K 3158, C07J 4300

Patent

active

054100402

ABSTRACT:
New monoquaternary and diquaternary 5-alpha-hydroxy-3,16-diaminoandrostane salts are disclosed with curare-like muscle relaxant activity. The new salts are characterized by a surprisingly rapid onset time.

REFERENCES:
patent: 3553212 (1971-01-01), Hewett et al.
patent: 4071515 (1978-01-01), Tuba et al.
patent: 4177190 (1979-12-01), Tuba et al.
Proceedings Of The Int'ntl Symposium On Instrumental High Performanc Thin-Layer Chromatography, 2nd, 1982 pp. 186-194, E. Janos et al.
Chem-Biol Interactions, 6, pp. 351-365 (1973).

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