Diamine derivatives as inhibitors of leukotriene A 4 hydrolase

Details Diamine derivatives as inhibitors of leukotriene A 4 hydrolase Diamine derivatives as inhibitors of leukotriene A 4 hydrolase

2006-12-22

2010-06-15

Wilson, James O (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S338000

Reexamination Certificate

active

07737145

ABSTRACT:
This invention is directed to compounds of formula (I):where r, q, R, R2, R3, R4, R5a, R5b, R5c, R6a, R6b, R6c, R7, R8, and R9are described herein, as single stereoisomers or as mixtures of stereoisomers, or pharmaceutically acceptable salts, solvates, clathrates, polymorphs, ammonium ions, N-oxides or prodrugs thereof; which are leukotriene A4hydrolase inhibitors and therefore useful in treating inflammatory disorders. Pharmaceutical compositions comprising the compounds of the invention and methods of preparing the compounds of the invention are also disclosed.

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