Diamine derivatives

Details Diamine derivatives Diamine derivatives

2003-12-25

2009-08-18

Seaman, D. Margaret (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

Reexamination Certificate

active

07576135

ABSTRACT:
A compound represented by formula (1):in-line-formulae description="In-line Formulae" end="lead"?Q1-Q2-T0-N(R1)-Q3-N(R2)-T1-Q4  (1)in-line-formulae description="In-line Formulae" end="tail"?[wherein R1and R2are hydrogen atoms or the like; Q1is a saturated or unsaturated, 5- or 6-membered cyclic hydrocarbon group which may be substituted, or the like; Q2is a single bond or the like; Q3represents the following group:(wherein Q5is an alkylene group having 1 to 8 carbon atoms, or the like); and T0and T1are carbonyl groups or the like], a salt thereof, a solvate thereof, or an N-oxide thereof.The compound is useful as an agent for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism, Buerger's disease, deep venous thrombosis, disseminated intravascular coagulation syndrome, thrombus formation after artificial valve or joint replacement, thrombus formation and reocclusion after angioplasty, systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), thrombus formation during extracorporeal circulation, or blood clotting upon blood drawing.

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