Dialysis process and system

Details Dialysis process and system Dialysis process and system

1993-09-15

1997-11-11

Kim, John

Liquid purification or separation

Processes

Liquid/liquid solvent or colloidal extraction or diffusing...

210 85, 2101952, 210645, 210805, 210929, 604 4, A61M 114, B01D 6100, B01D 6130, B01D 6132

Patent

active

056859880

ABSTRACT:
Disclosed is a method and apparatus for the quantification of solute removal during hemodialysis. The method relies upon discontinuing the flow of fresh dialysate to the dialyzer and recirculating the dialysate in a closed loop through the dialyzer. Recirculation is continued until a steady state concentration of solute (e.g. urea) in the dialysate is achieved. Analysis of the dialysate by suitable means at this time yields a value equal to the solute concentration in the blood without the need for blood sampling. Normal dialysis is resumed by discontinuing the recirculation and providing fresh dialysate to the dialyzer. Determination of solute concentrations at least at the beginning and end of the dialysis period allows the determination of solute loss and the quantification of dialysis therapy and its on-line prescription.

REFERENCES:
patent: 3669878 (1972-06-01), Marantz et al.
patent: 3669880 (1972-06-01), Marantz et al.
patent: 3822201 (1974-07-01), Waters et al.
patent: 3926734 (1975-12-01), Gray et al.
patent: 3989622 (1976-11-01), Marantz et al.
patent: 4036747 (1977-07-01), Mori et al.
patent: 4094775 (1978-06-01), Mueller
patent: 4213859 (1980-07-01), Smakman et al.
patent: 4508622 (1985-04-01), Polaschegg et al.
patent: 4923613 (1990-05-01), Chevallet
patent: 4990258 (1991-02-01), Bjare et al.
patent: 5024756 (1991-06-01), Sternby
patent: 5100554 (1992-03-01), Polaschegg
patent: 5110477 (1992-05-01), Howard et al.
patent: 5308315 (1994-05-01), Khuri et al.
patent: 5399157 (1995-03-01), Goux et al.
patent: 5405315 (1995-04-01), Khuri et al.
patent: 5518623 (1996-05-01), Keshaviah et al.
L.J. Garred et al., The International Journal of Artificial Organs, vol. 12, No. 2, pp. 96-102 (1989).
Malchesky et al., "Arrangement for the Direct Assessment of Solute Removal During Hemodialysis", Cleveland Clinic Foundation Invention and Discovery Disclosure (Jun., 1990).
"Direct Quantification of Dialysis", P. S. Malchesky, et al., Dialysis & Transplantation, vol. 11, No. 42 (1982) pp. 42-49.
"Urea Kinetic Modelling Based On Monitoring Urea In the Spent Dialysate Stream", L. J. Gerred et al. ASAIO 1990 Abs.
"KT/V & Protein Catabolic Rate Determination From Serial Urea Measurement In The Dialysate Effluent Stream", L. J. Garred et al., Art. Organs, vol. 16, No. 3, 1992, pp. 248-255.

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