1991-04-10
1993-03-09
Aschenbrenner, Peter A.
Surgery
Truss
Pad
604 29, 604 43, 604 96, 128768, A61M 2500
Patent
active
051919001
ABSTRACT:
A microdialysis probe for living tissue having respective inlet and outlet, fluid impermeable tubes connected by a dialysis fiber membrane permeable only to small molecular weight compounds. A U-shaped, loop probe tip configuration of the fiber membrane contains a biologically inert wire insertion to prevent kinking and ensure continuous fluid flow through the tip. The length and/or inner diameter of the outlet tube is selected with respect to a given flow rate to create an optimum positive fluid pressure inside the probe membrane tip sufficient to self-support the membrane during insertion and dialysis sampling. Alternative side-by-side and concentric probe configurations are described.
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Aschenbrenner Peter A.
The Board of Trustees of the University of Illinois
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