Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...
Patent
1996-07-31
1998-04-21
Rimell, Sam
Surgery
Means for introducing or removing material from body for...
Treating material introduced into or removed from body...
604158, 604161, A61M 5178
Patent
active
057412847
DESCRIPTION:
BRIEF SUMMARY
FIELD OF THE INVENTION
The invention relates to a dialysis probe combination, a microdialysis probe and an insertion device.
BACKGROUND OF THE INVENTION
By microdialysis is meant an investigatory procedure in which a probe is inserted in vivo in tissue, such that one side of a semi-permeable membrane will be in contact with tissue and body fluid, while the other side is flushed with a dialysis liquid which takes up substances through the membrane, wherewith these substances can then be analyzed in the liquid that flows past. A microdialysis probe is known from SE-C-434 214. This method has made significant advances over recent years, and the number of research publications that are connected with microdialysis have increased a thousand-fold in ten years.
The use in clinical and polyclinical activities for diagnostic purposes on human beings, however, has been retarded, primarily because dialysis probes are naturally quite fragile, which makes them difficult to insert. At least one part of the probe must have a surface which is comprised of a thin, semi-permeable membrane, which is easily broken.
U.S. Pat. No. 4,354,491 teaches single-slot canula tubes which after inserting a catheter into a vein can be withdrawn from the body, whereafter the outer part of the catheter can be withdrawn out of the slot. This patent publication also describes a canula tube which includes two mutually opposing, longitudinally extending slots of which one terminates immediately prior to the tip, and with which the two parts of the canula tube are held together at the other end by means of a separate fitting. However, neither solution can be used with a microdialysis catheter, due to the fact that it must include at its proximal end a connecting part for connection to an ingoing and an outgoing hose, this connector part being necessarily of larger diameter than the inner diameter of the canula tube. Thus, it is necessary in both cases to extend the catheter without increasing its diameter, which increases its dead volume.
It is also known to insert a plastic hose fitted on a stiffening metal canula tube having a cutting tip, this canula tube being withdrawn after insertion. A catheter can then be inserted in the hose and the hose, which can be readily torn along two generatrices, can then be withdrawn and pulled apart at weakenings provided to this end, so as to be eliminated.
In the case of the aforesaid known arrangement, which has been found usable for applying microdialysis probes, the work involved is relatively troublesome and requires the use of two hands for manoeuvering and splitting the canula tube or the hose and a further hand for preventing the microdialysis probe from accompanying the canula tube as the canula tube is withdrawn. The problems associated with insertion have therefore retarded the use of the microdialysis method for clinical and polyclinical examinations. An object of the present invention is to provide a microdialysis combination which will eliminate these difficulties and which will even make it possible for a patient or a relative to insert a microdialysis probe, something which has been unthinkable hitherto.
SUMMARY OF THE INVENTION
These and other objects and advantages are achieved in accordance with the invention with a dialysis probe combination according to the above that has the characteristic features set forth in the claims. According to the invention, a dialysis probe and a canula tube are used whose particular configuration makes the invention possible and which have the characterizing features set forth in the claims.
When applying the invention, a separate canula tube having an inwardly lying probe is inserted to the position in which the probe shall lie, possibly after having pierced the actual skin as a preparatory measure. During insertion the probe lies within the canula tube, wherewith at least the distal part of the probe and parts of its proximal part are sufficiently large to be unable to leave the canula tube through its longitudinally extending slot. When the canula tu
REFERENCES:
patent: 3359978 (1967-12-01), Smith
patent: 3472232 (1969-10-01), Earl
patent: 3584625 (1971-06-01), Swick
patent: 3603311 (1971-09-01), Huggins
patent: 3827434 (1974-08-01), Thompson et al.
patent: 4354491 (1982-10-01), Marbry
patent: 4377165 (1983-03-01), Luther
patent: 5106365 (1992-04-01), Hernandez
patent: 5441481 (1995-08-01), Mishra
CMA/Microdialysis Holding AB
Rimell Sam
Yeh Luke
LandOfFree
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