Diagnostics apparatus for determining precorneal retention time

Details Diagnostics apparatus for determining precorneal retention time Diagnostics apparatus for determining precorneal retention time

1996-06-27

1998-01-13

Azpuru, Carlos A.

Drug, bio-affecting and body treating compositions

Topical body preparation containing solid synthetic organic...

Ophthalmic preparation

424 7804, 514912, 514914, 514915, A61K 3174

Patent

active

057076146

ABSTRACT:
Apparatus and method for measuring ophthalmic formulation retention on the surface of an eye include dissolving a fluorescent macromolecule in an ophthalmic formulation to form a fluorescently labelled formulation; topically administering the fluorescently labelled formulation to an eye, said fluorescently labelled formulation forming a thin film on the eye surface. Apparatus is provided for illuminating the eye to cause fluorescence of the fluorescently labelled formulation as the fluorescently labelled formulation thin film is eliminated from the eye by normal blinking and lacrimation; and for measuring fluorescence from the thin film as a function of time.

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