Diagnostics and therapeutic uses of topors

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S006120

Reexamination Certificate

active

07632650

ABSTRACT:
The present invention relates to topors and its association with cancer. Topors antibodies are provided for use in diagnosing cancer based upon the absence of topors in a given cell or tissue sample. The detection of topors nucleic acid molecules in the diagnosis of cancer is also provided.

REFERENCES:
patent: 5798266 (1998-08-01), Quay et al.
OMIM entry # 609507 downloaded on May 16, 2009 from NCBI web site url>>> http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=609507.
NCBI Accession No: AF098300 [gi:4566494] with revision history—Apr. 6, 1999-Jun. 22, 1999.
Haluska et al., “Interaction between the N-terminus of human topoisomerase I and SV40 large T antigen”, Nucleic Acids Research 1998 26(7):1841-1847.
Zhou et al., “Identification of a novel gene encoding a p53-associated protein”, Gene 1999 235:93-101.

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