Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2011-03-08
2011-03-08
Aeder, Sean E (Department: 1642)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S007100
Reexamination Certificate
active
07901881
ABSTRACT:
The present invention relates to the use of genes differentially expressed in benign thyroid lesions and malignant thyroid lesions for the diagnosis and staging of thyroid cancer.
REFERENCES:
patent: 5556752 (1996-09-01), Lockhart et al.
patent: 5578832 (1996-11-01), Trulson et al.
patent: 5593839 (1997-01-01), Hubbell et al.
patent: 5599695 (1997-02-01), Pease et al.
patent: 5631734 (1997-05-01), Stern et al.
patent: 2004/0219521 (2004-11-01), Tang et al.
patent: 0 721 016 (1996-07-01), None
patent: 0 728 520 (1996-08-01), None
patent: 0 785 280 (1997-07-01), None
patent: 0 799 897 (1997-10-01), None
patent: 1 756 303 (2007-02-01), None
patent: WO 95/22058 (1995-08-01), None
patent: WO 97/02357 (1997-01-01), None
patent: WO 97/27317 (1997-07-01), None
patent: WO 97/29212 (1997-08-01), None
patent: WO 00/63438 (2000-10-01), None
patent: WO 03/025135 (2003-03-01), None
patent: WO 03/054152 (2003-07-01), None
patent: WO 03/065873 (2003-08-01), None
patent: WO 03/104427 (2003-12-01), None
patent: WO 2005/100608 (2005-10-01), None
Chory et al (PNAS, Nov. 1990, 87(22):8776-80).
Natali et al (Cancer Research, Apr. 1995, 55:1787-1791).
Tockman et al (Cancer Res., 1992, 52:2711s-2718s).
Greenbaum et al. (Genome Biology, 2003, vol. 4, Issue 9, pp. 117.1-117.8).
Le Roch et al (Genome Research, Nov. 2004, 14(11): 2308-2318).
Lichtinghagen et al (European Urology, 2002, 42:398-406).
Mazzaferri et al., “Long term impact of initial surgical and medical therapy on paillary and follicular thyroid cancer”, Am J Pathol, 97(5), 418-428, Nov. 1994.
Mazzaferri, E. L., “Management of a solitary thyroid nodule”, N. Engl. J. Med., 328(8), 553-559, Feb. 25, 1993.
Mazzanti et al., “Using gene expression profiling to differentiate benign versus malignant thyroid tumors”, Cancer Res., Apr. 15, 2004 64(8), 2898-2903.
Axelsson et al., “Global Tumor RNA Expression in Early Establishment of Experimental Tumor Growth and Related Angiogenesis following Cox-Inhibition Evaluated by Microarray Analysis”, Cancer Information, May 1, 2007, 3, 125-139.
Barden et al., “Classification of follicular thyroid tumors by molecular signature: results of gene profiling”, Clinical Cancer Reserach, 9(5), 1792-1800, May 2003.
Barker et al., “Human c-kit oncogene on human chromosome 4”, Am. J. Hum. Genet., 37, A143, 1985.
Becker et al., “E-Cadherin gene mutations provide clues to diffuse type gastric carcinomas”, Cancer Res., 54(14), 3845-3852, Jul. 15, 1994.
Caraway et al., “Diagnostic pitfalls in thyroid fine-needle aspiration: a review of 394 cases”, Diagn Cytopathol, 9(3), 345-350, 1993.
Cerutti et al., “A preoperative diagnostic test that distinguishes benign from malignant thyroid carcinoma based on gene expression”, J Clin Invest., Apr. 2004, 113(8), 1234-1242.
Cerutti et al., “Molecular profiling of matched samples identifies biomarkers of papillary thyroid carcinoma lymph node metastasis”, Cancer Res., Aug. 15, 2007, 67(16), 7885-7892.
Chee et al., “Accessing genetic information with high-density DNA arrays ”, Science, 274(5287), 610-614, Oct. 25, 1996.
De Miguel et al., “Dissection of the c-Kit signaling pathways in mouse primordial germ cells by retroviral- mediated gene transfer”, Proc. Nat. Acad. Sci., 99(16), 10458-10463, Aug. 16, 2002 Epub Jul. 24, 2002.
Durand et al., “Evaluation of gene expression profiles in thyroid nodule biopsy material to diagnose thyroid cancer”, J Clin Endocrinol Metab., Apr. 2008, Epub: Jan. 22, 2008, 93(4), 1195-1202.
Eberwine, J., “Amplification of mRNA populations using aRNA generated from immobilized oligo(dT)-T7 primed cDNA”, Biotechniques, 20(4), 584-591, Apr. 1996.
Eszlinger et al., “Perspectives and limitations of microarray-based gene expression profiling of thyroid tumors”, Endocr Rev., May 2007, Epub: Mar. 12, 2007, 28(3), 322-338.
Feldman et al., “Advantages of mRNA amplification for microarray analysis”, Biotechniques, 33(4), 906-912, 914, Oct. 2002.
Finley et al., “Discrimination of benign and malignant thyroid nodules by molecular profiling”, Ann Surg., Sep. 2004, discussion 436-437, 240(3), 425-36.
Finley et al., “Molecular profiling distinguishes papillary carcinoma from benign thyroid nodules”, J Clin Endocrinol Metab., Jul. 2004, 89(7), 3214-3223.
Fluge et al., “Gene expression in poorly differentiated papillary thyroid carcinomas”, Thyroid., Feb. 2006, 16(2), 161-175.
Fryknäs et al., “Molecular markers for discrimination of benign and malignant follicular thyroid tumors”, Tumour Biol., 2006, Epub: May 2, 2006, 27(4), 211-220.
GenBank Accession No. AB032954, Oct. 4, 1999.
GenBank Accession No. AL832414.1, Jan. 20, 2005.
GenBank Accession No. AP001717, Apr. 10, 2000.
GenBank Accession No. BC038512, Oct. 7, 2002.
GenBank Accession No. NM—000222, 1992.
GenBank Accession No. NM—001584, 1994.
GenBank Accession No. NM—004360, 1988.
GenBank Accession No. NM—004710, 1998.
GenBank Accession No. NM—006134, 1999.
GenBank Accession No. NM—014883, 1997.
GenBank Accession No. NM—016199, 1999.
GenBank Accession No. NM—018439, 2000.
GenBank Accession No. NP—060265, Aug. 11, 2003.
GenBank Accession No. X06182, 1987.
Gharib et al., “Fine-needle aspiration biopsy of the thyroid. The problem of suspicious cytologic findings”, Ann Intern Med, 101(1), Jul. 25-28, 1984.
Goellner et al., “Fine needle aspiration cytology of the thyroid, 1980 to 1986”, Acta Cytol, 31(5), 587-590, Sep.-Oct. 1987.
Goellner, J. R., “Problems and pitfalls in thyroid cytology”, Monogr Pathol, (39), 75-93, 1997.
Golub et al., “Molecular classification of cancer: class discovery and class prediction by gene expression monitoring”, Science, 286(5439), 531-537, Oct. 15, 1999.
Gordon et al., “Using gene expression ratios to predict outcome among patients with mesothelioma”, J Natl Cancer hist, 95(8), 598-605, Apr. 16, 2003.
Hacia et al., “Detection of heterozygous mutations in BRCA1 using high density oligonucleotide arrays and two-colour fluorescence analysis”, Nature Genetics 14(4), 441-447, Dec. 1996.
Hamberger et al., “Fine-needle aspiration biopsy of thyroid nodules. Impact on thyroid practice and cost of care”, Am J Med, 73(3), 381-334, Sep. 1982.
Hoos et al., “Clinical significance of molecular expression profiles of Hürthle cell tumors of the thyroid gland analyzed via tissue microarrays”, Am J Pathol., Jan. 2002, 160(1), 175-183.
Huang et al., “Gene expression in papillary thyroid carcinoma reveals highly consistent profiles”, Proc Natl Acad Sci U S A., 98(26), 15044-15049, Dec. 18, 2001.
Jarzimg id="CUSTOM-CHARACTER-00001" he="2.12mm" wi="1.78mm" file="US07901881-20110308-P00001.TIF" alt="custom character" img-content="character" img-format="tif" ?b et al., “Gene expression profile of papillary thyroid cancer: sources of variability and diagnostic implications”, Cancer Res., Feb. 15, 2005, 65(4), 1587-1597.
Khan et al., “Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks”, Nat Med., Jun. 2001, 7(6), 673-679.
Kozal et al., “Extensive polymorphisms observed in HIV-1 clade B protease gene using high-density oligonucleotide arrays”, Nature Medicine 2(7),753-759, Jul. 1996.
Lockhart et al., “Expression monitoring by hybridization to high-density oligonucleotide arrays”, Nature Biotechnology 14(13), 1675-1680, Dec. 1996.
Lubitz et al., “Microarray analysis of thyroid nodule fine-needle aspirates accurately classifies benign and malignant lesions”, J Mol Diagn., Sep. 2006, quiz 528, 8(4), 490-498.
Mazzaferri et al., “Long term impact of initial surgical and medical therapy on paillary and follicular thyroid can
Libutti Steven K.
Mazzanti Chiara
Umbricht Christopher
Zeiger Martha
Aeder Sean E
The John Hopkins University
The United States of America as represented by the Department of
Woodcock & Washburn LLP
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