Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1986-03-21
1989-03-21
Rosen, Sam
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 7, 435820, 435948, 436510, 436519, 436809, 436813, G01N 33554, G01N 33569, G01N 33571, G01N 33574
Patent
active
048142697
ABSTRACT:
A method of testing a fluid sample for the presence of antibodies against a micro-organism, which comprises contacting the sample with fixed cells or fragments of cells infected with the micro-organism, and determining the presence of antibody bound to the cell-associated antigens, in which the determination is by virtue of a color change visible to the naked-eye at the site of the antibodies. For use in a testing method of this type, a test component comprises upper and lower layers, in which the upper layer has an array of apertures through which discrete areas on the lower layer are exposed, and in which the lower layer carries, in some at least of the discrete areas, fixed cells or cell fragments infected by a micro-organism.
REFERENCES:
patent: 4520113 (1985-05-01), Gallo et al.
patent: 4588681 (1986-05-01), Sawada et al.
patent: 4607008 (1986-08-01), Coates et al.
Dal Conte et al, Journ. of Infection, 16, 263-272, 1988.
Karpas et al, The Lancet, Jul. 18, 1987, pp. 132-133.
Werner et al, The Lancet, Nov. 9, 1985, p. 1065.
M. Naiem et al, Journ. Immunol. Meth., 50, 145-160, 1982.
G. Gerna, in G. Feldmann et al (Eds.), Immunoenzymatic Techniques, North-Holland Publishing Co., Amsterdam, 1976, pp. 443-449.
D. Y. Mason et al, in G. R. Bullock et al (Eds.), Techniques in Immunocytochemistry, Academic Press, New York, 1983, pp. 175-195.
M. Naiem et al, Biol. Abstr., 75, Abstr. No. 41879, 1983.
Kuhlman, W. D., "Immuno Enzyme Techniques in Cytochemistry," 1st Edition, pp. 61-67, Verlag Chemie, Basel, CH; 1984.
Popovic et al., M. , "Detection, Isolation and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS," Science 224, pp. 497-500, May 4, 1984, Washington, U.S.
Cenfold Holdings S.A.
Rosen Sam
Saunders David A.
LandOfFree
Diagnostic testing for antibodies against microorganisms does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Diagnostic testing for antibodies against microorganisms, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Diagnostic testing for antibodies against microorganisms will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-476702