Diagnostic test strip

Details Diagnostic test strip Diagnostic test strip

1992-04-03

1994-03-22

Alexander, Lyle A.

Chemical apparatus and process disinfecting, deodorizing, preser

Analyzer, structured indicator, or manipulative laboratory...

Calorimeter

422 58, 436 63, 436164, 436805, G01N 2100

Patent

active

052961923

ABSTRACT:
Disclosed is a multi-layered test strip device for receiving whole blood on which a test for a suspected analyte is performed. The test confirms the presence, absence, or the amount of analyte, if present. The multi-layered device comprises two outside support layers between which are, in descending order relative to the horizontal plane, a) a spreading screen having defined characteristics, b) a separating layer which removes red blood cells at least partially via a red blood cell binding agent, and c) a membrane reagent layer; wherein the screen and each layer is in close and contiguous contact with the layer which follows it, and wherein at least one of layers a), b), and c) is conditioned by a pre-treatment.
The screen can have openings of from 10-200 microns. The blood cell binding agents are antibodies to red blood cells, chemical agents, or lectins. The separating layer has screen opening of preferably 20-200 microns.

REFERENCES:
patent: 4987085 (1991-01-01), Allen et al.

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