Diagnostic test method

Details Diagnostic test method Diagnostic test method

1974-06-03

1977-01-25

Padgett, Benjamin R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Attached to antibody or antibody fragment or immunoglobulin;...

23230B, 232306, G01N 3300, G01T 116, G21H 502

Patent

active

040051870

ABSTRACT:
A method of measuring a diagnostically significant component in a fluid test sample in which the desired component is selectively adsorbed by a solid adsorbent formed, in situ, in the sample, the amount of the component then being determined by a suitable technique such as, for example, radioassaying. In a preferred embodiment, the invention is directed to thyroid function testing in which the in situ formed solid adsorbent is used to selectively adsorb the free thyroid hormone in the test serum, the amount of thyroid hormone and/or the unsaturated binding capacity of thyroid hormone binding protein being determined by radioassaying methods employing radioisotope labeled thyroid hormone as a tracer.

REFERENCES:
patent: 3666854 (1972-05-01), Eisentraut
patent: 3776698 (1973-12-01), Eisentraut
patent: 3793445 (1974-02-01), Updike et al.
patent: 3799740 (1974-03-01), Mincey
Mitchell et al, Journal of Clinical Endocrinology and Metabolism, vol. 20, Nov, 1960, pp. 1474-1483.
Murphy et al., Journal of Clinical Endocrinology and Metabolism, vol. 24, Feb., 1964, pp. 187-196.

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