Diagnostic test kits

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S005000, C435S007100, C435S069200, C435S069300

Reexamination Certificate

active

11175605

ABSTRACT:
This invention provides kits, devices, and methods for the detection of antibodies that recognize one or more proteins and/or antigens from porcine reproductive and respiratory syndrome virus (PRRSV). The antibodies may be in a biological fluid of a PRRSV infected or at risk subject. The invention may be advantageously applied to both the diagnosis and prevention of PRRSV infection.

REFERENCES:
patent: 4562147 (1985-12-01), Joo
patent: 5690940 (1997-11-01), Joo
patent: WO99/39583 (1999-08-01), None
Choi et al., Relative sensitivity and specificity of agar gel immunodiffusion, enzyme immunosorbent assay, and immunoblotting for detection of anti-bovine leukemia virus antibodies in cattle, Journal of Virological Methods, 2002, vol. 104, pp. 33-39.
Plagemann, Epitope specificity of monoclonal antibodies to the N-protein of porcine reproductive and respiratory syndrome virus determined by ELISA with synthetic peptides, Veterinary Immunology and Immunopathology, 2005, vol. 104, pp. 59-68.
Giuseppe et al., Expression of Bovine Leukemia Virus Envelope Glycoprotein (gp51) by Recombinant Baculovirus and Its Use in an Enzyme-Linked Immunosorbent Assay, Clinical and Diagnostic Laboratory Immunology, Jan. 2004, vol. 11, No. 1, pp. 147-151.
Dea S., et al. “Current knowledge on the structural proteins of PRRS virus: comparison of the N. American and European isolates”,Arch Virol(2000) 145:659-688.
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Kim, H.S., et al. “Enhanced replication of porcine reproductive and respiratory syndrome virus in a homogeneous subpopulation of MA-104 cell line”,Arch Virol(1993) 133:477-483.
Cho, H. J., et al. “An ELISA for Porcine Reproductive and Respiratory Syndrome: Production of Antigen of High Quality”,Can. J. Vet. Res. (1996) 60:89-93.
Cho, H. J., et al. “Performance of ELISA Antigens Prepared from 8 Isolates of Porcine Reproductive and Respiratory Syndrome Virus with Homologous and Heterologous Antisera”,Can. J. Vet. Res. (1997) 61:299-304.
IDEXX: “Trousse de Détection de Anticorps dirigés contre le Virus du Syndrome Dysgénésique et Respiratoire Porcine (SDRP/PRRS)”, IDEXX, XP002412193 (Dec. 14, 2001) pp. 5-9.
Albina, E. “Le syndrome dysgénésique et respiratoire porcin: dix ans d'expérience (1986-1996) sur une infection virale insolite”,Vet Res. (1997) 28(4):305-352.
Denac, Helena, et al. “An indirect ELISA for the detection of antibodies against porcine reproductive and respiratory syndrome virus using recombinant nucleocapsid protein as antigen”,Journal of Virological Methods(1997) 65(2):169-181.

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