Chemistry: analytical and immunological testing – Cancer
Reexamination Certificate
2011-08-23
2011-08-23
Wallenhorst, Maureen (Department: 1777)
Chemistry: analytical and immunological testing
Cancer
C436S063000, C436S086000, C436S094000
Reexamination Certificate
active
08003392
ABSTRACT:
Described are methods and kits to detect early stage hepatocellular carcinoma or a change in the gradation of hepatocellular carcinoma in mammals. The diagnostic marker is based on the profiling and identification of diagnostic carbohydrates present in a body fluid, such as blood serum.
REFERENCES:
patent: 2004/0147033 (2004-07-01), Shriver et al.
patent: 2005/0112691 (2005-05-01), Callewaert et al.
patent: 2006/0014294 (2006-01-01), Contreras et al.
patent: 2008/0318332 (2008-12-01), Mechref et al.
patent: WO 2006/121892 (2006-11-01), None
patent: WO 2008/152070 (2008-12-01), None
patent: 2009/013538 (2009-01-01), None
patent: 2009/075883 (2009-06-01), None
patent: 2009/117666 (2009-09-01), None
#Callewaert et al., Noninvasive diagnosis of liver cirrhosis using DNA sequencer-based total serum protein glycomics, Nature Medicine, Nature Publishing Group, Apr. 1, 2004, pp. 429-34, vol. 10, No. 4, New York, NY, US.
#Paradis et al., Identification of a New Marker of Hepatocellular Carcinoma by Serum Protein Profiling of Patients With Chronic Liver Disease, Hepatology, 2005, pp. 40-47, vol. 41, No. 1.
#Comunale et al., Proteomic Analysis of Serum Associated Fucosylated Glycoproteins in the Development of Primary Hepatocellular Carcinoma, Journal of Proteome Research, 2006, pp. 308-15, vol. 5, No. 2.
#Liu et al., N-Glycomic Changes in Hepatocellular Carcinoma Patients with Liver Cirrhosis Induced by Hepatitis B Virus, Hepatology, 2007, pp. 1426-1435, vol. 46, No. 5.
PCT International Search Report, PCT/EP2008/057325, dated Sep. 23, 20008.
U.S. Appl. No. 12/231,168, filed Aug. 28, 2008, Contreras et al., Improved Protein Secretion in Eukaryotic Cells.
U.S. Appl. No. 11/792,203, filed Aug. 6, 2007, Chen et al., Aging Biomarker.
U.S. Appl. No. 12/225,396, filed Sep. 17, 2008, Contreras et al., Novel Vaccine Against Trypanosoma Cruzi Infection.
European Office Action of Application No. 08 760 873.3-2404; dated Nov. 3, 2010.
Response to Office action dated Feb. 24, 2011.
Chen Cuiying
Contreras Roland H.
TraskBritt P.C.
Universiteit Gent
VIB VZW
Wallenhorst Maureen
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