Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1998-04-30
2000-08-08
LeGuyader, John L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 911, 536 231, 536 2431, 536 2433, C12Q 168, C07H 2104
Patent
active
061000337
ABSTRACT:
A a diagnostic test useful for prenatal identification of Down syndrome and mental retardation. A method for gene therapy for correction and treatment of Down syndrome. DYRK gene involved in the ability to learn. A method for diagnosing Down's syndrome and mental retardation and an assay therefor. A pharmaceutical composition for treatment of Down's syndrome mental retardation.
REFERENCES:
Song et al (Genomics 38:331-339, 1996.
Joo et al (J Biotechnol. 35(2-3):135-53, 1994.
Simpson et al, Ann. NY Acad. Sci. 731:1-8, 1994.
Rubin Edward M.
Smith Desmond J.
Aston David J.
Kaushal Sumesh
LeGuyader John L.
Mahoney John W.
Martin Paul R.
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