Diagnostic technique for rheumatoid arthritis

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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435 7, 436509, 436804, 436808, 424 15, 435240, 435241, 435244, 435810, 435 2, G01N 3348, G01N 3358, C12N 502

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044029349

ABSTRACT:
A method for diagnosis of rheumatoid arthritis and related diseases comprises determination of polyclonal lymphocyte activation in B-cells cultured in the presence of patient serum. A diagnostic kit is also provided.

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Cohen, P. L. and 21FF, M., J. of Immunol., vol. 119, No. 4, 10-77, "Abnormal Polyclonal B Cell Activation in N2V/N2WF, Mice".
Teodorescu, M. et al., Clin. Res., vol. 27, pp. 694aff, 1979, "Polyclonal B Cell Activator in the Serum of Patients with Rheumatic Diseases".
Buchholz, D. M. et al., Immunology, vol. 37, p. 731, 08-79 "Dependence of Lymphocyte Surface on Continuous Polyclonal Activation".
Buchholz, D. M. et al., Cellular Immunology, vol. 44, p. 209-1979, "T-Dependent but not T-Dependent Antigens Maintain Surface Ig . . . ".

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