Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure
Patent
1980-12-15
1983-05-24
Nucker, Christine M.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Molecular bilayer structure
424 9, 536 21, A61K 4900, A61K 4300, C08B 3708
Patent
active
043850464
ABSTRACT:
A novel class of chelated radio-labeled polysaccharide derivatives are useful for diagnosing formed, and forming, blood clots in a vascular system. Novel intermediate metal-binding compounds comprise a water-soluble polysaccharide moiety having an average of at least 0.25 anionic groups per monosaccharide unit, and at least one chelating group derived from amino acids, substituted cyclic acid anhydrides, or carbon disulfide. The intermediate compound is then reacted with a radioactive tracer metal compound.
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Barnett William E.
Ferber Richard H.
Milbrath Dean S.
Alexander Cruzan
Minnesota Mining and Manufacturing Company
Nucker Christine M.
Sell Donald M.
Sherman Lorraine R.
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