Diagnostic methods for mycoplasma genitalium infections

Details Diagnostic methods for mycoplasma genitalium infections Diagnostic methods for mycoplasma genitalium infections

1990-02-16

1992-10-27

Kepplinger, Esther L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 79, 435 794, 43524027, 435975, 5303884, 5303913, 530809, 935 95, G01N 33569, C07K 1528

Patent

active

051588706

ABSTRACT:
Monoclonal antibodies binding Mycoplasma genitalium more strongly than Mycoplasma pneumoniae, Mycoplasma hominis, Mycoplasma orale, Mycoplasma salivarium and Acholeplasm laidlawii are described herein. These monoclonal antibodies are utilized in immunoassays directed toward the detection of M. genitalium infections. Hybridomas producing the above-described monoclonal antibodies have been created and isolated. These monoclonal antibodies are directed toward M. genitalium antigens. Certain antibodies bind protein antigens, while others bind lipid antigens. In one case a particular antibody apparently has binding affinity for both protein and lipid antigens of M. genitalium.

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