Diagnostic methods

Details Diagnostic methods Diagnostic methods

1989-10-02

1992-08-11

Jaworski, Francis

Surgery

Truss

Pad

A61B 1000

Patent

active

051370301

ABSTRACT:
A probe is provided for collecting mucous tissue samples in vivo particularly from the conjunctiva, the urethra and the cervix. The probe comprises a handle portion and a body portion, which is slotted for scraping tissue into the slots.
The tissue sample may then be introduced into an aqueous transport medium comprising sucrose, potassium phosphates, foetal bovine serum, streptomycin, vancomycin and nystatin. The sample may be smeared from the transport medium, with the cells still intact onto a slide, using a cytocentrifuge; and then the smear is assayed for disease, for example disease due to adenovirus, herpes simplex virus or chlamydia.
The assay step may include single or multiple immunofluorescent staining.

REFERENCES:
patent: 3540432 (1970-11-01), Ayre
patent: 3724463 (1973-04-01), Vail
patent: 3838681 (1974-10-01), Dalton
patent: 3877464 (1975-04-01), Vermes
patent: 4027658 (1977-06-01), Marshall
patent: 4448205 (1984-05-01), Stenkvist
patent: 4757826 (1988-07-01), Abdulhay

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