Chemistry: analytical and immunological testing – Biological cellular material tested
Reexamination Certificate
2007-06-12
2009-11-03
Wallenhorst, Maureen M (Department: 1797)
Chemistry: analytical and immunological testing
Biological cellular material tested
C436S071000, C436S094000, C435S006120, C435S975000, C536S023100
Reexamination Certificate
active
07611902
ABSTRACT:
This invention provides a diagnostic method for determining statin induced myopathy. The method is especially applicable for determining warnings, early signs and also symptomatic myopathy. The method includes collecting a lipidomic profile from a biological sample such as blood or serum and comparing the obtained lipidomic profile to reference lipidomic markers. The reference lipidomic markers have been established by combining a pro-inflammatory muscle tissue gene expression profile with a lipidomic profile associated with high dosage statin treatment. This invention also relates to a kit for performing a method for determining statin induced myopathy.
REFERENCES:
patent: 2003/0224470 (2003-12-01), Phillips
patent: 2005/0009005 (2005-01-01), Watkins
patent: 2007/0202518 (2007-08-01), Ruano et al.
patent: WO03/005628 (2003-01-01), None
patent: 2007/061995 (2007-05-01), None
Laaksonen et al. PLoS One, vol. e97, issue 1, Dec. 2006, pp. 1-9.
“An Assessment of Statin Safety by Muscle Experts,” Thompson et al., The American Journal of Cardiology (www.AJConline.org), vol. 97(8A), Apr. 17, 2006.
“High-dose statins and skeletal muscle metabolism in humans: A randomized, controlled trial,” Hannu Paiva et al., Clinical Pharmacology & Therapeutics, Jul. 2005.
Laaksonen Reijo
Lehtimäki Terho
Oresic Matej
Päivä Hannu
Wallenhorst Maureen M
Young & Thompson
Zora Biosciences Oy
LandOfFree
Diagnostic method for myopathy does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Diagnostic method for myopathy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Diagnostic method for myopathy will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4123115