Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1998-08-13
2000-11-07
Stucker, Jeffrey
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 74, 435 79, 435 792, 435 794, 435 795, 435 23, 436518, 436531, 436516, G01N 3353
Patent
active
061435066
ABSTRACT:
The invention relates to methods and test kits for diagnosis of periodontal disease activity in mammals, especially in human. The methods of the invention provide for rapid chair-side diagnosis of periodontitis, peri-implantitis and HIV (+)-infection/AIDS-disease related periodontal diseases. Especially, the methods of the invention provide for rapid chair-side diagnosis of the loss of bone density associated with periodontal diseases.
REFERENCES:
patent: 5736341 (1998-04-01), Sorsa et al.
Golub et al. "A matrix metalloproteinase inhibitor reduces bone-type collagen degradation fragments and specific collagenases in gingival crevicular fluid during adult periodontitis", Inflammation Research, vol. 46, No. 8(Aug. 1997) pp. 310-319. RM1.A3.
Harlow et al. Antibodies: A Laboratory Manual. N.Y., Cold Spring Harbor, 1988. pp. 8, 141, 142, 555 and 556. QR186.7.A53.
Uitto, V.J., Airola, K., Vaalamo, M., Johansson, N., Putnins, E.E., Firth, J.D., Salonen, J., Lopez-Otin, C., Saarialho-Kere, U., Kahari, V-M, "Matrix Metalloproteinase-13 is a Major Collagenase in Inflamed Human Gingiva", Journal of Dental Research, 77:Abstract No. 2904 (1998).
Giannobile, W.V., Lee, H.M., Ryan M.E., Golub L.M., "Low Dose Doxcycline (LDD) Reduces Bone-type Collagen Degradation Fragments in Gingival Fluid", Journal of Dental Research, 76:Abstract No. 1306 (1997).
Golub Lorne M.
Sorsa Timo
Teronen Olli
Tikanoja Sari Hannele
Stucker Jeffrey
The Research Foundation of State of NY
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