Diagnostic method for alzheimer's disease based on...

Chemistry: analytical and immunological testing – Biological cellular material tested

Reexamination Certificate

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C436S086000, C536S026400, C514S052000

Reexamination Certificate

active

10332041

ABSTRACT:
The invention provides a diagnostic or prognostic assay method for Alzheimer's Disease by assaying a body fluid sample or a test sample derived therefrom for holo-trancobalamin II.

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patent: 6417006 (2002-07-01), Sundrehagen
patent: WO 00/17659 (2000-03-01), None
Johnston et al. Journal of the American Geriatrics Society, vol. 45 (6), Jun. 1997, pp. 779-780.
Clarke Robert et al: “Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease.” Archives of Neurology, vol. 55, No. 11, Nov. 1998, pp. 1449-1455.
Kristensen Marianne O et al: “Serum cobalamin and methymalonic acid in Alzheimer dementia.” ACTA Neurologica Acandinavica, vol. 87, No. 6, 1993, pp. 475-481.
Basun Hans et al: “Cobalamin levels are not reduced in Alzheimer's disease: Results from a population-based study.” Journal of the American Geriatrics Society, vol. 42, No. 2, 1994, pp. 132-136.

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