Chemistry: analytical and immunological testing – Pregnancy or ovulation
Reexamination Certificate
2008-07-15
2008-07-15
Gabel, Gailene R (Department: 1641)
Chemistry: analytical and immunological testing
Pregnancy or ovulation
C422S067000, C435S007100, C435S007500, C435S007920, C435S007940, C436S501000, C436S518000, C436S524000, C436S528000, C436S065000, C436S547000, C436S548000, C530S387500, C530S388240, C530S389200
Reexamination Certificate
active
07399636
ABSTRACT:
The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG is a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.
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Cole, L., Kardana, A., Andrade-Gordon, P., Gawinowicz, M., Morris, J., Bergert, E., O'Connor, J. and Birken, S. (199
Birken Steven
Kovalevskaya Galina I.
O'Connor John F.
Cooper & Dunham LLP
Gabel Gailene R
The Trustees of Columbia University in the City of New York
White John P.
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