Diagnostic immunoassay methods using monoclonal antibody F36/22

Details Diagnostic immunoassay methods using monoclonal antibody F36/22 Diagnostic immunoassay methods using monoclonal antibody F36/22

1989-09-18

1997-07-29

Hutzell, Paula K.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 794, 435344, 4353441, 53038885, G01N 3353, C07K 1630, C12N 520

Patent

active

056521146

ABSTRACT:
Monoclonal antibodies to adenocarcinoma cells, and, in particular, breast carcinoma cells, are produced by a hybridoma formed by fusing mouse lymphocytes and mouse myeloma cells. The monoclonal antibodies are capable of shrinking solid human breast tumors xenografted in nude mice. The monoclonal antibodies identify an antigen associated with carcinomas of ductal lineage. The monoclonal antibodies, specifically, F36/22 monoclonal antibodies, can be used diagnostically and therapeutically.

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