Diagnostic genes for toxoplasmosis

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 2432, 435 6, 4352523, 43525233, 4353201, 935 12, 935 72, 935 73, 935 78, C07H 2100, C12N 120, C12N 1500

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056294140

ABSTRACT:
Genetic material encoding p30 and B1 peptides of Toxoplasma gondii has been isolated and characterized. This genetic material allows the production of peptides for use in diagnosis or immunization or can itself be directly used in hybridization assays.

REFERENCES:
patent: 4358535 (1982-11-01), Falkow et al.
Kasper et al., J. Immunol. 130:2407 (1983).
Huynh et al., In "DNA Cloning", ed. Glover, vol. 1:49 (1985).
J.L. Burg et al., "Molecular Cloning and Analysis of Genes Encoding Toxoplasma gondii Antigens" J. Cell. Biochem., 10A:145 (1986).
J.L. Burg et al., "Molecular Analysis of the Gene Encoding the Major Surface Antigen of Toxoplasma gondii" J. of Immunology, 141:3580-3591 (1988).
Boothroyd et al., UCLA Symp. Mol. Cell. Biol. New Ser. vol. 42:237-50 (1987).
Johnson et al., Expt. Parasit. 63:272-278 (1987).

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