Diagnostic device for the detection of increased dehydrogenase o

Details Diagnostic device for the detection of increased dehydrogenase o Diagnostic device for the detection of increased dehydrogenase o

1983-08-15

1988-02-09

Warden, Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving oxidoreductase

435 25, 435 27, 435 28, 604361, 604362, 604904, C12Q 132, A61F 1316

Patent

active

047242043

ABSTRACT:
A diagnostic device for the detection of an increased concentration of dehydrogenases and/or oxidases in the fluids of humans, animals or plants, which consists of a carrier which bonds a redox dyestuff, and a substance mixture, adjusted to a pH value in the acid range, of the substrate corresponding to the particular dehydrogenase, a hydrogen donor compound and at least one redox dyestuff is described. The device has the peculiarity that the carrier contains polar groups and the substance mixture for detecting exclusively pathologically increased concentrations of the particular dehydrogenase and/or oxidase is adjusted to a pH value of below 5.0. The device is suitable for diagnosing malignant growths in very different organs, for example in the female genital area.

REFERENCES:
patent: 4266022 (1981-05-01), Lamprecht
Tietz, et al., Fundamentals of Clinical Chemistry, 1976, W. B. Saunders Co., pp. 576-580, 652-654.

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