Diagnostic device for fecal occult blood and method of use

Chemistry: physical processes – Physical processes – Crystallization

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23931, 252408, 422 56, 422 61, 435184, G01N 2178, G01N 3372

Patent

active

043337341

ABSTRACT:
Diagnostic test device for fecal occult blood utilizing a test matrix such as paper impregnated with guaiac. False-positive results in the presence of peroxidases are prevented by adding to the matrix a compound that cleaves protein hydrogen bonds such as guanidine hydrochloride and a chelating agent that binds calcium and/or magnesium such as EDTA.

REFERENCES:
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patent: 2990338 (1961-06-01), Gibson
patent: 3917452 (1975-11-01), Rittersdorf et al.
patent: 3996006 (1976-12-01), Pagano
patent: 4017261 (1977-04-01), Svoboda et al.
Henry, "Clinical Chemistry--Principles and Techniques", Harper and Row, 1964, New York, pp. 78-785.
Mahler et al., "Biological Chemistry", Harper and Row, New York, 1966, pp. 117-120.

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