Diagnostic device for fecal occult blood and method of use

Details Diagnostic device for fecal occult blood and method of use Diagnostic device for fecal occult blood and method of use

1980-10-08

1982-06-08

Turk, Arnold

Chemistry: physical processes

Physical processes

Crystallization

23931, 252408, 422 56, 422 61, 435184, G01N 2178, G01N 3372

Patent

active

043337341

ABSTRACT:
Diagnostic test device for fecal occult blood utilizing a test matrix such as paper impregnated with guaiac. False-positive results in the presence of peroxidases are prevented by adding to the matrix a compound that cleaves protein hydrogen bonds such as guanidine hydrochloride and a chelating agent that binds calcium and/or magnesium such as EDTA.

REFERENCES:
patent: 2905594 (1959-09-01), Morris
patent: 2990338 (1961-06-01), Gibson
patent: 3917452 (1975-11-01), Rittersdorf et al.
patent: 3996006 (1976-12-01), Pagano
patent: 4017261 (1977-04-01), Svoboda et al.
Henry, "Clinical Chemistry--Principles and Techniques", Harper and Row, 1964, New York, pp. 78-785.
Mahler et al., "Biological Chemistry", Harper and Row, New York, 1966, pp. 117-120.

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