Diagnostic device and manufacture thereof

Details Diagnostic device and manufacture thereof Diagnostic device and manufacture thereof

1976-12-20

1978-05-23

Marantz, Sidney

Chemistry: physical processes

Physical processes

Crystallization

23230B, 23259, 156664, 424 12, G01N 3316

Patent

active

040908496

ABSTRACT:
Clinically useful diagnostic devices are prepared from commercially available metal sheet stock by a sequence of steps. The metal is one of a type on the surface of which a tenacious oxide layer can be produced. Steps in the preparation include roughening surface area of the bulk metal with pits on a fine scale to render that surface area of the metal non-specularly reflecting, chemically etching the surface area to produce some first preselected measure of reflectivity, anodizing the surface area to produce a dull, non-specularly reflecting oxide surface having a second preselected degree of reflectivity and applying a layer of protein over this dull surface area. The preferred metal is titanium and the reflectivity of the modified surface area is selected dependent on the immunological reaction being detected.

REFERENCES:
patent: 3853467 (1974-12-01), Giaever
patent: 3926564 (1975-12-01), Giaever
patent: 3979184 (1976-09-01), Giaever
patent: 3979509 (1976-09-01), Giaever
patent: 4041146 (1977-08-01), Giaever
patent: 4054646 (1977-10-01), Giaever

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