Diagnostic compositions comprising a complex formed by a nitroge

Details Diagnostic compositions comprising a complex formed by a nitroge Diagnostic compositions comprising a complex formed by a nitroge

1995-01-12

1997-07-08

Kight, John

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

424 942, 534 15, 534 16, A61K 4900

Patent

active

056458185

ABSTRACT:
The invention relates to ligands having the formula (I), in which X represents a heterocyclic group, together with the process for their preparation. The invention also concerns mono- or polymetallic complexes formed by said ligands with metallic ions selected from lanthanide ions, transition metal ions, barium ion, bismuth ion, lead ion and the radioisotopes 99m.sub.Tc, 111.sub.In, 90.sub.Y, 64.sub.Cu and 169.sub.Yb, as well as salts physiologically acceptable to these complexes. The salts of said complexes can be used as diagnostic and therapeutic agents in magnetic resonance imaging, radiology, in vivo chemical displacement agents and in nuclear medicine.

REFERENCES:
patent: 4920195 (1990-04-01), Kankare et al.
patent: 5057302 (1991-10-01), Johnson et al.
patent: 5059412 (1991-10-01), Simon et al.
patent: 5334371 (1994-08-01), Gries et al.
patent: 5364613 (1994-11-01), Sieving et al.
patent: 5373093 (1994-12-01), Vallarino et al.
patent: 5374416 (1994-12-01), Rousseaux et al.
patent: 5385893 (1995-01-01), Kiefer
patent: 5417960 (1995-05-01), Schaefer et al.
patent: 5480990 (1996-01-01), Kiefer et al.
H. Stetter et al., "Darstellung und Komplexbildung von Polyazacycloalkan -N-Essigsauren", Tetrahedron, vol. 37, pp. 767-772, 1981.
Newkome et al., "Octahedral Complexes Derived from a Hexaaza-18-crown-6 Ligand: 3,6,12,15-Tetramethyl-18{N(2,6)-Pyridino, N-1,2,1].sub.2 -coronand-6}", Inorganica, Chimica Acta, 77(1983), L47-L49.

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