Diagnostic composition for radiologic imaging of neoplasms in th

Details Diagnostic composition for radiologic imaging of neoplasms in th Diagnostic composition for radiologic imaging of neoplasms in th

1981-10-30

1985-02-19

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 9, 26024591, A61K 2900, A61K 4900

Patent

active

045005079

ABSTRACT:
A novel chemical method of labeling porphyrin compounds, specifically hematoporphyrin derivative (HPD), with the radionuclide Technetium-99m producing a radioactive tracer material suitable for biomedical applications. HPD labeled with .sup.99m Tc is biologically active in vivo and is preferentially taken up by neoplastic tissues. This provides a simple and specific means of visualizing tumors in man or animal by scintigraphic imaging techniques.

REFERENCES:
Sanderson et al., Cancer, vol. 30, (1972): 1368-1372.
Bases et al., Cancer, vol. 11, (1958): 259-263.
Lipson et al., J. Natl. Cancer Inst., vol. 26, (1961): 1-11.

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