Diagnostic assays using nucleic acid probes

Details Diagnostic assays using nucleic acid probes Diagnostic assays using nucleic acid probes

1990-07-06

1999-11-09

Horlick, Kenneth R.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

435 6, 435 911, C12Q 170, C12Q 168, C12P 1934

Patent

active

059811714

ABSTRACT:
Methods and compositions are provided for a rapid quantitative nucleic acid hybridization assay for detecting a DNA or RNA sequence in a biological sample. The method comprises solution hybridization of a target nucleic acid sequence with a detectably-labeled probe, separation of the target-nucleic acid probe from the unhybridized probe by gel exclusion or affinity chromatography and detection of the amount of labeled probe as an indication of the target nucleic acid present in the biological sample.

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