Diagnostic assays and kits for RNA using RNA binary probes and a

Details Diagnostic assays and kits for RNA using RNA binary probes and a Diagnostic assays and kits for RNA using RNA binary probes and a

1994-12-12

1998-09-15

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435912, 435 9121, 435 9131, 435 9151, 435 9152, 435810, 536 2432, 536 2431, 935 16, 935 17, 935 78, C12Q 168, C12P 1934, C07H 2104

Patent

active

058076743

ABSTRACT:
There are provided nucleic acid hybridization assays for RNA targets using RNA binary probes and a protein that is an RNA-directed RNA ligase. Preferred assays include generation of an exponentially amplified signal. Most preferred assays include T4 DNA ligase as the RNA-directed RNA ligase. Also provided are kits for performing assays according to this invention.

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