Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2006-08-22
2006-08-22
Zara, Jane (Department: 1635)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S091100, C435S091500, C536S023100, C536S023500, C536S024310, C536S024330, C536S025320
Reexamination Certificate
active
07094538
ABSTRACT:
The lifetime probability of a person developing cancer can now be determined based on an allelic variation found in the 3′UTR of the prohibitin gene. The probability is dependent on the sequence of the 3′UTR at position 729, i.e., whether there is a thymine (T) or a cytosine (C) or both at this position. Determining the sequence at the position 729 can be done by any number of standard techniques. Preferably, the sequence is determined by amplifying this region by PCR and subjecting it to an RFLP analysis.
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Dell'Orco Robert T.
Jupe Eldon R.
Resta Regina
Thompson Linda F.
Fulbright & Jaworski
Oklahoma Medical Research Foundation
Zara Jane
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